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Back to all News. Share on Social. A possible concern related to COVID stems from the notion that these blood pressure medications could increase the number of ACE2 receptors expressed on cells, possibly creating more molecular gates for the virus to enter. Some experts have wondered whether the use of such drugs could render people who take them more susceptible to infection. Conversely, others have postulated that the abundance of ACE2 receptors may enhance cardiovascular function, exercising a protective effect during infection.
The answer is far from clear, but a recent review suggests these medicines may play a dual role in COVID — on the one hand, enhancing susceptibility to infection and, on the other, protecting the heart and ameliorating lung damage from the disease. Libby and Ridker cautioned that patients who take such life-saving medications should stay on them or at least have a careful discussion with their cardiologists.
This is because these drugs have clear and well-established benefits in hypertension and certain forms of heart disease, while their propensity to make humans more susceptible to SARS-CoV-2 remains speculative for the time being.
But what remains speculative today will crystalize in the weeks and months to come, Ridker and Libby said, because the science is moving forward rapidly, with new papers coming out daily and a growing pool of patients to draw observations from. Health Services director Giang Nguyen talks about adding remote services and new resources for Harvard community.
New projections suggest social-distancing measures in state may be flattening the curve. The need for rigorous randomized trials done quickly and effectively is acute, they said.
Until the evidence from these trials begins to coalesce, clinicians will have to navigate the uncharted territory of delivering cardiac care in the time of pandemic with caution but also with resolve. Ofer Levy right and David Dowling are working toward developing age-specific vaccines. COVID may spark cardiac trouble in multiple ways.
Love, death, fear, guilt, pride, hope, friendship, alienation, and so much sorrow. Through it all, they kept showing up. How does the new coronavirus stoke cardiac damage? The frenemy within For Ridker and Libby, the cardiac involvement in COVID is yet another striking example of the widespread effects of inflammation on multiple organs and systems. By phone and online, the care continues Health Services director Giang Nguyen talks about adding remote services and new resources for Harvard community.
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